Members of B-shift were dispatched to the area of the 8 mile marker on Eastbound I-275 for a reported auto accident with extrication. Upon arrival units found a two vehicle accident with one subject trapped in the vehicle. The other vehicle was not occupied at the time of the accident. The trapped occupant was extricated but unfortunately succumbed to his injuries. E-351, E-352, S-364 and S-365 all responded to this incident.